Hero Image


Informed decisions.
Safer choices.

Understanding CBD is key to knowing what it can do. CBMD® gathers resources and research to help physicians and consumers understand what’s in the products they use.


Year CBD was first isolated and identified by Harvard chemist Roger Adams.


Percent of US doctors that have discussed CBD/cannabis with their patients.


Amount of US doctors who feel they know enough about CBD to advise their patients on product selection or utility.

What is CBD?

Cannabidiol (CBD) is one of 113 biologic compounds—called cannabinoids—found within the trichomes of the cannabis/hemp plant. Two of the most well-known of these compounds are CBD and THC. While both are naturally occurring, CBD is distinct from THC, in that CBD does not produce the psychoactive effect (or high) that THC does.

All cannabinoid molecules, like those found in CBD, act on the receptors in the body's endocannabinoid system (ECS). Active in the body whether or not a person uses CBD or THC products, the ECS plays a role in sleep, appetite, mood, memory, and immune processes.

All CBMD products are formulated with broad-spectrum CBD, which has been purified to substantially reduce the THC content and profile.


Different types of CBD

Today, one can find CBD labeled full-spectrum, broad-spectrum, and pure isolate. Full-spectrum products contain precisely that: the full range of both cannabinoids and terpenes present in the plant. (Terpenes are the chemicals responsible for the smell and taste associated with cannabis). Full-spectrum products are notable in that they are inclusive of THC.

However, by definition, CBD cannot contain more than 0.3% of THC. On the other hand, broad-spectrum products are refined so as to remove much more of the THC content and profile. CBD isolate is created by extracting CBD and then removing all other cannabinoids and terpenes, isolating only the CBD molecules.



Determining the appropriate CBD dose is dependent upon a number of factors, including the delivery technology, concentration, and product type. There are also other factors to consider, like a person's unique biological makeup, and medicines an individual might be taking, Additionally, CBD isolate will exert a different kind of dose response than broad-spectrum and full-spectrum products. Because of this variability, we recommend that individuals consult a doctor, and also begin with a low dosage and build from there.



The term bioavailability refers to the percentage or fraction of a given dose that is absorbed into the bloodstream, and therefore made available for use by the body. Bioavailability is based on a variety of factors, including product composition and method of delivery. In several of our CBD formulations, we incorporate ingredients that display increased and prolonged bioavailability.


Endocannabinoid System

All cannabinoid molecules, like those found in CBD, act on the receptors in the body's endocannabinoid system (ECS). Active in the body whether or not a person uses CBD or THC products, the ECS plays a role in sleep, appetite, mood, memory, and immune processes.

There are two main kinds of receptors: CB1 receptors, which are mainly concentrated in the brain, and CB2 receptors, located throughout the body and largely connected with immune system function.

The human body also produces its own endocannabinoids, a fact that is part of an interesting story of the endocannabinoid system's scientific provenance—starting in the early 19th century and leading to the recent mapping of the endocannabinoid receptors' genetic group.

Feel better with PMT today
CBD Types Dosing Bioavailability Endocannabinoid
Image With text

Our partnership

A common purpose.

CBMD™ operates in association with Cannabiomed™, a consortium of medical professionals, researchers, scientists, and pharmacists working to bring a medical perspective to the CBD industry.

Cannabiomed™ seeks to equip healthcare practitioners with resources that enable them to be informed, effective advisors for patients wanting to integrate CBD into their wellness routines.

Learn more

Featured publication

and research

Created by Americans for Safe Access (ASA),The Patient's Guide to CBD is an informative resource for patients, healthcare providers, consumers, and others seeking information on the topic of cannabidiol (CBD).

Open PDF

Additional resources

Extra blog image

FDA recommends science-based approach

With so many questions around the safety and quality of CBD products, the FDA looks at policy to ensure safe standards are maintained for the production of CBD.

Read more
Extra blog image

Clinicians guide to CBD and hemp oil

With the explosion in CBD’s popularity comes the need for physicians to understand the importance of product selection to ensure safety.

Read more
Extra blog image

Johns Hopkins professor looks to physicians

Associate Professor of Psychiatry and Behavioral Sciences Ryan Vandrey, PhD says patients should speak to their doctors before trying CBD.

Read more
FAQ banner


What makes PMT Pain Topical Cream different from other CBD products?

PMT Topical Cream is a medical grade CBD product formulated by physicians with deep experience in pain science and musculoskeletal conditions. CBMD’s sole focus is on developing the highest quality pain support products. CBMD prioritizes researched based formulations, quality ingredient sourcing, rigorous testing protocols, and transparent and accurate labeling.

Is PMT right for me?

PMT is suitable for individuals seeking topical pain support. It's ideal for those looking for a natural alternative to traditional alternatives like NSAIDs or pharmaceutical pain options.

PMT Topical Cream is used by individuals looking for support with muscle soreness, injury, or generalized joint or muscle discomfort. PMT Topical Cream should not be used by children, pregnant or breastfeeding women, or individuals with liver or kidney disorders. It should not be used on open wounds or broken skin.

We recommend consulting with our support team or your healthcare professional to determine if PMT is suitable for your specific needs.

How should I use PMT Topical Cream?

We recommend applying PMT Topical Cream twice daily, although many patients use it as needed. A typical application consists of a 1-gram or nickel-sized amount, which should be gently massaged into the skin for optimal absorption. For specific usage instructions, please refer to the product label.

What ingredients are in PMT Topical Cream?

At CBMD, quality and transparency are paramount to us. We carefully select each high quality ingredient in our formulations.

Purified Water (Aqua), Organic Aloe Barbadensis (Aloe) Inner Leaf Juice, Organic Carthamus Tinctorius (Safflower) Seed Oil, Organic Symphytum Officinale (Comfrey) Root Extract, Caprylic/Capric Triglyceride, Cetearyl Glucoside, Cetearyl Olivate, Glycerin, Salix Alba (White Willow) Bark Extract, Organic Zingiber Officinale (Ginger) Root Extract, Cetearyl Alcohol, Capsicum Annuum (Cayenne Pepper) Extract, Arnica Cordifolia (Arnica) Flower Extract, Sorbitan Olivate, Organic Simmondsia Chinensis (Jojoba) Seed Oil, Xanthan Gum, Glyceryl Caprylate, Broad Spectrum Hemp CBD Oil, Mentha Spicata (Spearmint) Oil, Mentha Piperita (Peppermint) Oil, MSM (Methylsulfonylmethane), Melaleuca Alternifolia (Tea Tree) Oil, Glyceryl Oleate, Niacinamide (Vitamin B3), Tocopherols (mixed Vitamin E), Glyceryl Stearate, Eucalyptus Globulus Leaf Oil, Caprylhydroxamic Acid, Potassium Olivoyl Hydrolyzed Oat Protein, Leuconostoc/Radish Root Ferment Filtrate, Potassium Sorbate.

If you have any questions about PMT Topical Cream or its ingredients, please don’t hesitate to contact us at info@cbmd.com

Is there THC in PMT Topical Cream?

PMT Topical Cream contains 0.0 THC. CBMD rigorously tests all products by third party laboratories to confirm these results.

Can PMT be used by athletes, clinicians, teachers, or law enforcement?

Generally yes, PMT can be used by individuals from various professions. However, the rules and regulations regarding the use of CBD products vary among athletics programs, educational institutions, and law enforcement agencies. We recommend checking with the specific organization to determine their policy on CBD products. Many organizations permit the use of CBD products with 0.0 THC, such as PMT Topical Cream.

What kinds of testing do CBMD products undergo?

CBMD products undergo comprehensive testing, including third-party lab testing for potency, purity, and quality assurance. We are committed to providing products that meet the highest standards.

Does PMT Topical Cream contain NSAIDs?

No, PMT Topical Cream does not contain NSAIDs (nonsteroidal anti-inflammatory drugs).